Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239129 | 1.00 | GRIN2B (0.30) | GRIN2BGRIN2CDPP4 | |
| SCHEMBL82277 | 0.95 | — | — | |
| SCHEMBL933448 | 0.84 | — | — | |
| SCHEMBL3190616 | 0.83 | — | — | |
| SCHEMBL1150703 | 0.83 | — | — | |
| SCHEMBL1150705 | 0.83 | — | — | |
| SCHEMBL17801011 | 0.81 | DGAT1 (0.33) | — | |
| SCHEMBL17259076 | 0.79 | HSD11B1 (0.36) | — | |
| SCHEMBL7438886 | 0.79 | NPSR1 (0.33) | — | |
| SCHEMBL15855789 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102482269-B | Proline derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (CN) | 2015-07-29 | — | — | CN | disclosed |
| EP-2692726-A1 | Anti-viral compounds | Abbvie Inc. (US) | 2014-02-05 | — | — | EP | disclosed |
| CN-102482269-A | Proline derivatives | NAT HEALTH RESEARCH INSTITUTES | 2012-05-30 | — | — | CN | disclosed |
| EP-2368890-A1 | Hepatitis C virus inhibitors | Abbott Laboratories (US) | 2011-09-28 | — | — | EP | disclosed |