SCHEMBL2367485

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@H](C(=O)N[C@H](CO)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](C)O

nearest known ligand 0.38

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	6/20	0.38

▸	VIPR1	P32241	3/20	0.38

▸	KISS1R	Q969F8	5/20	0.37

▸	NPY1R	P25929	3/20	0.37

▸	VIPR2	P41587	3/20	0.37

▸	TASP1	Q9H6P5	1/20	0.36

▸	NPY2R	P49146	2/20	0.35

▸	NPY5R	Q15761	2/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2366674	0.94	RXFP1 (0.41)	NPY4R
SCHEMBL2367091	0.93	RXFP1 (0.41)	NPY4RVIPR1NPY1RVIPR2NPY2R
SCHEMBL2366814	0.91	RXFP1 (0.42)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL2367748	0.90	RXFP1 (0.38)	NPY4RVIPR1NPY1RVIPR2NPY5R
SCHEMBL2368042	0.90	RXFP1 (0.44)	NPY4RNPY1RNPY2RNPY5R
SCHEMBL13723928	0.90	KISS1R (0.43)	NPY4RVIPR1KISS1RNPY1RVIPR2
SCHEMBL16357955	0.90	KISS1R (0.43)	NPY4RVIPR1KISS1RNPY1RVIPR2
SCHEMBL3046711	0.89	RXFP1 (0.40)	NPY4RVIPR1NPY1RVIPR2NPY2R
SCHEMBL2367832	0.89	RXFP1 (0.37)	NPY4R
SCHEMBL2368091	0.89	RXFP1 (0.40)	NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed