SCHEMBL2367748

CC[C@H](C)[C@H](NC(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@H](C(=O)N[C@H](C)C(=O)N[C@H](C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](OC(=O)C(F)(F)F)C(N)=O)[C@H](C)O

nearest known ligand 0.39

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	RXFP1	Q9HBX9	1/20	0.38

▸	VIPR2	P41587	5/20	0.38

▸	VIPR1	P32241	3/20	0.38

▸	NPY4R	P50391	3/20	0.38

▸	MAPK8	P45983	1/20	0.37

▸	MAPK9	P45984	1/20	0.37

▸	MAPK10	P53779	1/20	0.37

▸	NPY5R	Q15761	3/20	0.37

▸	NPY1R	P25929	2/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367485	0.90	NPY4R (0.38)	VIPR2VIPR1NPY4RNPY5RNPY1R
SCHEMBL2368091	0.89	RXFP1 (0.40)	RXFP1NPY4R
SCHEMBL2367091	0.88	RXFP1 (0.41)	RXFP1VIPR2VIPR1NPY4RMAPK8
SCHEMBL2367050	0.88	RXFP1 (0.42)	RXFP1VIPR2VIPR1NPY4RNPY5R
SCHEMBL2367400	0.88	RXFP1 (0.40)	RXFP1VIPR2VIPR1NPY4R
SCHEMBL2367032	0.88	RXFP1 (0.40)	RXFP1VIPR2VIPR1NPY4R
SCHEMBL3046711	0.87	RXFP1 (0.40)	RXFP1VIPR2VIPR1NPY4RNPY5R
SCHEMBL2366814	0.86	RXFP1 (0.42)	RXFP1NPY4RNPY5RNPY1R
SCHEMBL2368042	0.85	RXFP1 (0.44)	RXFP1NPY4RNPY5RNPY1R
SCHEMBL2367433	0.85	NPY4R (0.40)	RXFP1NPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed