Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367366 | 0.94 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367560 | 0.93 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10661639 | 0.92 | THRB (0.46) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL10663710 | 0.91 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367991 | 0.91 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL35511 | 0.91 | TSHR (0.51) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15702196 | 0.90 | THRB (0.47) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15702182 | 0.88 | THRB (0.49) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL5948162 | 0.88 | THRB (0.53) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL12396077 | 0.88 | THRB (0.51) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288496-B2 | Contact lens and its manufacturing method | NIPPON CONTACT LENS INC. (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20110237701-A1 | CONTACT LENS AND ITS MANUFACTURING METHOD | NIPPON CONTACT LENS INC. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-2369370-A2 | Contact lens and its manufacturing method | Nippon Contact Lens Inc. (JP) | 2011-09-28 | — | — | EP | disclosed |
| US-4602074-A | SILICON CONTAINING ACRYLIC MONOMER | NIPPON CONTACT LENS MANUFACTURING LTD. (JP) | 1986-07-22 | — | — | US | disclosed |