Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2367570

C[C@H](NC(=O)OCc1ccccc1)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.58
ATM Q13315 1/20 0.56
CTSK P43235 5/20 0.56
MME P08473 1/20 0.56
ECE1 P42892 1/20 0.56
CTSL P07711 3/20 0.55
CTSS P25774 3/20 0.55
CTSB P07858 2/20 0.54
CTRB1 P17538 2/20 0.53
ALDH1A1 P00352 1/20 0.52
ALOX15 P16050 1/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
KMT2A Q03164 1/20 0.52
ITGB3 P05106 1/20 0.52
ITGA2B P08514 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241565 0.91 CTSK (0.61) CAPN1ATMCTSKMMEECE1
SCHEMBL241564 0.91 CTSK (0.61) CAPN1ATMCTSKMMEECE1
SCHEMBL856196 0.91 CTSK (0.61) CAPN1ATMCTSKMMEECE1
Hydrochloric Acid SCHEMBL7400990 0.90 CTSK (0.60) CAPN1ATMCTSKMMEECE1
Hydrochloric Acid SCHEMBL7400995 0.90 CTSK (0.60) CAPN1ATMCTSKMMEECE1
SCHEMBL7421757 0.86 CTSK (0.62) CAPN1ATMCTSKMMEECE1
Glycolic Acid SCHEMBL901392 0.86 CTSK (0.56) CAPN1ATMCTSKMMEECE1
SCHEMBL10954146 0.86 CTSK (0.62) CAPN1ATMCTSKMMEECE1
SCHEMBL22475275 0.86 CTSK (0.62) CAPN1ATMCTSKMMEECE1
SCHEMBL8177898 0.86 CTSK (0.62) CAPN1ATMCTSKMMEECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2007794-B1 LYSOBACTIN AMIDES AICURIS GMBH & CO KG (DE) 2011-09-14 EP disclosed
WO-1998043962-A1 HETEROCYCLIC INTEGRIN INHIBITOR PRODRUGS DU PONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO disclosed