SCHEMBL856196

SCHEMBL856196

C[C@@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.61
CTSL P07711 1/20 0.61
CTSB P07858 1/20 0.61
CTSS P25774 1/20 0.61
ATM Q13315 1/20 0.61
MME P08473 1/20 0.59
ECE1 P42892 1/20 0.59
CAPN1 P07384 1/20 0.59
MEN1 O00255 1/20 0.59
LMNA P02545 1/20 0.59
KMT2A Q03164 1/20 0.59
CTRB1 P17538 2/20 0.57
ELANE P08246 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241565 1.00 CTSK (0.61) CTSKCTSLCTSBCTSSATM
SCHEMBL241564 1.00 CTSK (0.61) CTSKCTSLCTSBCTSSATM
Hydrochloric Acid SCHEMBL7400995 0.98 CTSK (0.60) CTSKCTSLCTSBCTSSATM
Hydrochloric Acid SCHEMBL7400990 0.98 CTSK (0.60) CTSKCTSLCTSBCTSSATM
SCHEMBL8177898 0.94 CTSK (0.62) CTSKCTSLCTSBCTSSATM
Glycolic Acid SCHEMBL901392 0.94 CTSK (0.56) CTSKCTSLCTSBCTSSATM
SCHEMBL22475275 0.94 CTSK (0.62) CTSKCTSLCTSBCTSSATM
SCHEMBL7421757 0.94 CTSK (0.62) CTSKCTSLCTSBCTSSATM
SCHEMBL10954146 0.94 CTSK (0.62) CTSKCTSLCTSBCTSSATM
Alanine SCHEMBL11300392 0.94 CTSK (0.56) CTSKCTSLCTSBCTSSATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 WO claimed
CN-112110834-A Modified hydrophobic auxiliary material and preparation method and application thereof 浙江智达药业有限公司 2020-12-22 CN claimed
EP-0118105-A2 2-Cyanosteroids G.D. Searle & Co. (US) 1984-09-12 EP claimed
US-4459235-A 2-Cyanosteroids G. D. SEARLE & CO. (US) 1984-07-10 US claimed
JP-57028099-A None JP disclosed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 US disclosed
EP-4692089-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AS AAK1 INHIBITOR Alicorn Pharmaceutical Co., Ltd. (CN) 2026-02-11 EP disclosed
EP-4656201-A2 RAS INHIBITORS Revolution Medicines, Inc. (US) 2025-12-03 EP disclosed
US-20250360205-A1 NOD1 MODULATORS AND USES THEREOF ACADEMIA SINICA (TW) 2025-11-27 US disclosed
US-20250195521-A1 USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS Revolution Medicines, Inc. 2025-06-19 US disclosed
CN-120058739-A Cycloalkyl-or haloalkyl-containing compounds 正大天晴药业集团股份有限公司 2025-05-30 CN disclosed
US-4174312-A ACYLATION, HYDROLYSIS, SALT FORMATION, CATALYTIC HYDROGENATION ABBOTT LABORATORIES (US) 1979-11-13 US disclosed
US-4173564-A 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A ABBOTT LABORATORIES (US) 1979-11-06 US disclosed
EP-0002039-A1 Phosphonous acid derivatives, processes for their preparation and their use in combating microorganisms CIBA-GEIGY AG (CH) 1979-05-30 EP disclosed
US-4155902-A ACYLATION, HYDROGENOLYSIS ABBOTT LABORATORIES (US) 1979-05-22 US disclosed
US-4091032-A ANTIMICROBIAL AGENTS ABBOTT LABORATORIES (US) 1978-05-23 US disclosed
US-4087520-A Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides BOEHRINGER MANNHEIM GMBH (DT) 1978-05-02 US disclosed
US-4012367-A Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto G. D. SEARLE & CO. (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP CTSK 2251/4885CTSL 1366/4885CTSB 1304/4885
US-20250195521-A1 USE OF SOS1 INHIBITORS TO TREAT MALIGNANCIES WITH SHP2 MUTATIONS SOS1, PPM1D, PTPN1 CTSK 3524/4885CTSL 4005/4885CTSB 3608/4885
US-20250360205-A1 NOD1 MODULATORS AND USES THEREOF NOD1, TLR1, NOD2 CTSK 4192/4885CTSL 3108/4885CTSB 2745/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CTSK 4188/4885CTSL 1811/4885CTSB 3814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.