Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.55 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852673 | 0.81 | DPP4 (0.47) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL12291405 | 0.81 | TGM2 (0.45) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2367543 | 0.80 | DPP4 (0.42) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL5355999 | 0.78 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5346118 | 0.77 | DPP4 (0.57) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14558294 | 0.76 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14558297 | 0.76 | DPP4 (0.52) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL2859755 | 0.74 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859760 | 0.74 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL10078258 | 0.71 | DPP4 (0.66) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | claimed |
| WO-2011113895-A2 | CHARACTERIZATION AND VALIDATION OF INHIBITORS AND LIGANDS OF DIPEPTIDYL AMINOPEPTIDASE IV (DP IV) | IMTM GMBH (DE) | 2011-09-22 | — | — | WO | disclosed |
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | disclosed |