Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 17/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12291405 | 0.88 | TGM2 (0.45) | DPP4DPP8DPP9DPP7FOLH1 | |
| SCHEMBL2367694 | 0.80 | DPP4 (0.55) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8355096 | 0.77 | TGM2 (0.40) | DPP4DPP8DPP9DPP7FOLH1 | |
| SCHEMBL8357427 | 0.71 | DPP4 (0.34) | DPP4DPP8DPP9DPP7FOLH1 | |
| SCHEMBL13852683 | 0.70 | TGM2 (0.38) | DPP4DPP8DPP9DPP7FOLH1 | |
| SCHEMBL10078265 | 0.70 | TGM2 (0.46) | DPP4DPP8DPP9DPP7TGM2 | |
| SCHEMBL10054478 | 0.70 | TGM2 (0.46) | DPP4DPP8DPP9DPP7TGM2 | |
| SCHEMBL5350152 | 0.70 | TGM2 (0.47) | DPP4DPP8DPP9DPP7TGM2 | |
| SCHEMBL2859552 | 0.68 | DPP4 (0.66) | DPP4DPP8DPP9DPP7TGM2 | |
| SCHEMBL2859559 | 0.68 | DPP4 (0.66) | DPP4DPP8DPP9DPP7TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | claimed |
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | disclosed |