Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL2367680 | 0.98 | LMNA (0.38) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| SCHEMBL27967282 | 0.84 | — | — | |
| SCHEMBL44010 | 0.84 | — | — | |
| SCHEMBL27811224 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL11497228 | 0.82 | — | — | |
| SCHEMBL27602312 | 0.82 | — | — | |
| SCHEMBL5964870 | 0.82 | — | — | |
| Phosphoric Acid SCHEMBL3926567 | 0.80 | USP2 (0.43) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| Phosphoric Acid SCHEMBL27624463 | 0.80 | LMNA (0.40) | SMN1; SMN2LMNAALDH1A1KDM4EDUSP3 | |
| Glycerin SCHEMBL14482185 | 0.79 | LMNA (0.60) | SMN1; SMN2LMNAALDH1A1KDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368433-B1 | Biocide compositions comprising glycerol(ether)phosphates | COGNIS IP MAN GMBH (DE) | 2014-05-07 | — | — | EP | claimed |
| WO-2011116891-A1 | BIOCIDE COMPOSITIONS COMPRISING GLYCEROL(ETHER)PHOSPHATES | COGNIS IP MANAGEMENT GMBH (DE) | 2011-09-29 | — | — | WO | claimed |
| EP-2368433-A1 | Biocide compositions comprising glycerol(ether)phosphates | Cognis IP Management GmbH (DE) | 2011-09-28 | — | — | EP | claimed |