Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599341 | 0.90 | SCN9A (0.44) | SSTR4AAK1SCN9AMAPK1CYP1A2 | |
| SCHEMBL19673352 | 0.85 | SSTR4 (0.39) | SSTR4AAK1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL17428846 | 0.83 | SSTR4 (0.45) | SSTR4AAK1SCN9ACYP1A2CYP3A4 | |
| SCHEMBL23677235 | 0.82 | SSTR4 (0.40) | SSTR4AAK1SCN9A | |
| SCHEMBL15599218 | 0.81 | SSTR4 (0.47) | SSTR4AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24599916 | 0.80 | SSTR4 (0.44) | SSTR4AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL22746004 | 0.77 | SSTR4 (0.41) | SSTR4AAK1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL15599216 | 0.76 | SCN9A (0.44) | SSTR4AAK1SCN9ACYP3A4 | |
| SCHEMBL17244897 | 0.75 | SCN9A (0.42) | AAK1SCN9AMAPK1 | |
| SCHEMBL15599221 | 0.75 | PTGS2 (0.51) | SSTR4AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854782-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |