Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.54 |
| ▸ | CA2 | P00918 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21626409 | 0.86 | LMNA (0.63) | MEN1KMT2AGRM4HTR2BSIRT2 | |
| SCHEMBL15612960 | 0.82 | HTR2B (0.60) | CA1CA2MEN1KMT2ACA9 | |
| SCHEMBL23677205 | 0.81 | HTR2B (0.57) | CA1CA2MEN1KMT2ACA9 | |
| SCHEMBL21844863 | 0.81 | KCNK3 (0.61) | MEN1KMT2AGRM4POLB | |
| SCHEMBL21623212 | 0.81 | GRM4 (0.49) | CA1CA2MEN1KMT2AGRM4 | |
| SCHEMBL15280081 | 0.80 | SIRT2 (0.53) | MEN1KMT2AGRM4HTR2BSIRT2 | |
| SCHEMBL15575769 | 0.80 | MEN1 (0.69) | CA1CA2MEN1KMT2ACA9 | |
| SCHEMBL15280019 | 0.80 | KMT2A (0.58) | MEN1KMT2ASIRT2LMNASMN1; SMN2 | |
| SCHEMBL18407921 | 0.79 | GRM4 (0.47) | CA1CA2MEN1KMT2AGRM4 | |
| SCHEMBL28312150 | 0.78 | MEN1 (0.65) | CA1CA2MEN1KMT2ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |