Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.60 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.60 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850239 | 0.84 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2850241 | 0.84 | DPP4 (0.53) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14392720 | 0.81 | DPP4 (0.75) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL29989745 | 0.80 | MGLL (0.65) | DPP8DPP9MGLLFAAHTRPV1 | |
| SCHEMBL2847975 | 0.78 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2847977 | 0.78 | DPP4 (0.65) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14558299 | 0.77 | DPP4 (0.58) | DPP4DPP7DPP8DPP9MGLL | |
| SCHEMBL19412173 | 0.76 | MGLL (0.84) | MGLLFAAHTRPV1 | |
| SCHEMBL2855429 | 0.76 | DPP7 (0.50) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2367715 | 0.76 | DPP4 (0.48) | DPP4DPP7DPP8DPP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | claimed |
| EP-2366394-A1 | Characterization and validation of inhibitors and ligands of dipeptidyl aminopeptidase IV (DP IV) | IMTM GmbH (DE) | 2011-09-21 | — | — | EP | disclosed |