Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.58 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367718 | 0.77 | DPP4 (0.60) | DPP4DPP7DPP8DPP9MGLL | |
| SCHEMBL14558294 | 0.77 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL14558297 | 0.74 | DPP4 (0.52) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2367694 | 0.71 | DPP4 (0.55) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859760 | 0.70 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859755 | 0.70 | DPP4 (0.58) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859625 | 0.70 | DPP7 (0.69) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL2859627 | 0.70 | DPP7 (0.69) | DPP4DPP7DPP8DPP9 | |
| SCHEMBL27802853 | 0.70 | FAAH (0.67) | MGLLFAAH | |
| SCHEMBL2859960 | 0.69 | DPP4 (0.51) | DPP4DPP7DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |