Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677258 | 0.84 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL23677151 | 0.82 | GRM4 (0.52) | SMN1; SMN2TP53LMNAHTTTLR7 | |
| SCHEMBL23677224 | 0.81 | GRM4 (0.53) | RAB9ANPC1SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL23677215 | 0.77 | CA1 (0.54) | CA1CA2CA9SMN1; SMN2BRAF | |
| SCHEMBL23677187 | 0.76 | CA1 (0.47) | CA1CA2CA9RAB9ASMN1; SMN2 | |
| SCHEMBL4117988 | 0.71 | IDO1 (0.48) | RAB9ANPC1SMN1; SMN2TSHRIDO1 | |
| SCHEMBL149098 | 0.71 | MEN1 (0.63) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL147440 | 0.70 | IDO1 (0.65) | CA1CA2CA9RAB9ANPC1 | |
| SCHEMBL20560649 | 0.70 | IDO1 (0.47) | CA2RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL17202417 | 0.69 | CES2 (0.35) | CA1CA2CA9SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |