Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.54 |
| ▸ | CA2 | P00918 | 16/20 | 0.54 |
| ▸ | CA9 | Q16790 | 9/20 | 0.54 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677279 | 0.89 | CA1 (0.57) | CA1CA2CA9ALDH1A1 | |
| SCHEMBL23677187 | 0.88 | CA1 (0.47) | CA1CA2CA9BRAFIDO1 | |
| SCHEMBL23677178 | 0.86 | CA1 (0.53) | CA1CA2CA9MEN1ALDH1A1 | |
| SCHEMBL23677261 | 0.83 | GRM4 (0.51) | CA1CA2CA9 | |
| SCHEMBL23677190 | 0.77 | CA1 (0.40) | CA1CA2CA9BRAFIDO1 | |
| SCHEMBL15612963 | 0.77 | HTR2B (0.52) | CA1CA2CA9IDO1MEN1 | |
| SCHEMBL23677278 | 0.76 | RAB9A (0.49) | CA1CA2CA9MEN1ALDH1A1 | |
| SCHEMBL15847680 | 0.76 | RAB9A (0.49) | CA1CA2CA9MEN1ALDH1A1 | |
| SCHEMBL21670961 | 0.74 | IDO1 (0.41) | CA1CA2CA9IDO1MEN1 | |
| SCHEMBL3525663 | 0.72 | CA1 (0.44) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |