Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677149 | 0.90 | SCN9A (0.38) | SCN9AKCNH2MRGPRX4XDHPTGDR2 | |
| SCHEMBL19411383 | 0.84 | SCN9A (0.51) | SCN9AKCNH2MRGPRX4XDHPTGDR2 | |
| SCHEMBL19429991 | 0.83 | SCN9A (0.63) | SCN9AKCNH2MRGPRX4XDHPTGDR2 | |
| SCHEMBL19411409 | 0.79 | SCN9A (0.46) | SCN9AKCNH2MRGPRX4XDHPTGDR2 | |
| SCHEMBL19411404 | 0.79 | SCN9A (0.51) | SCN9ASCN7ASCN5A | |
| SCHEMBL22912670 | 0.78 | SCN9A (0.44) | SCN9AKCNH2MRGPRX4SCN7ASCN5A | |
| SCHEMBL23677146 | 0.73 | SCN9A (0.67) | SCN9ASCN7ASCN5A | |
| SCHEMBL23677150 | 0.67 | SCN9A (0.46) | SCN9AKCNH2 | |
| SCHEMBL16239866 | 0.65 | SCN9A (0.60) | SCN9ASCN5A | |
| SCHEMBL17423019 | 0.63 | SCN9A (0.82) | SCN9ASCN7ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854782-A1 | SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2021-07-28 | — | — | EP | disclosed |