Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 14/20 | 0.50 |
| ▸ | CA2 | P00918 | 14/20 | 0.50 |
| ▸ | CA9 | Q16790 | 8/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | WRN | Q14191 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23677279 | 0.85 | CA1 (0.57) | CA1CA2CA9 | |
| SCHEMBL23677215 | 0.83 | CA1 (0.54) | CA1CA2CA9 | |
| SCHEMBL23677178 | 0.81 | CA1 (0.53) | CA1CA2CA9 | |
| SCHEMBL21623212 | 0.79 | GRM4 (0.49) | GRM4CA1CA2CA9 | |
| SCHEMBL21337289 | 0.79 | GRM4 (0.43) | GRM4CA1CA2CA9LRRK2 | |
| SCHEMBL21524055 | 0.79 | GRM4 (0.47) | GRM4CA1CA2CA9BLM | |
| SCHEMBL22916247 | 0.78 | GRM4 (0.42) | GRM4CA1CA2CA9LRRK2 | |
| SCHEMBL23677224 | 0.78 | GRM4 (0.53) | GRM4LRRK2BLMWRN | |
| SCHEMBL15612926 | 0.77 | HTR2B (0.50) | GRM4LRRK2 | |
| SCHEMBL21623540 | 0.77 | CYP1A2 (0.65) | GRM4CA1CA2CA9LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890375-B1 | SULFAMOYL-ARYLAMIDES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-07-28 | — | — | EP | disclosed |