Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29044405 | 0.70 | SPR (0.38) | LMNATSHRHPGDCYP2C19ALOX15 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL18422 | 0.67 | HPGD (0.67) | LMNATSHRHPGDCYP2C19ALOX15 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL29572496 | 0.67 | HPGD (0.67) | LMNATSHRHPGDCYP2C19ALOX15 | |
| SCHEMBL9468166 | 0.66 | LIG1 (0.40) | LMNATSHRHPGDCYP2C19ALOX15 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL11145317 | 0.65 | LIG1 (0.64) | LMNATSHRHPGDCYP2C19ALOX15 | |
| SCHEMBL455832 | 0.65 | LIG1 (0.64) | LMNATSHRHPGDCYP2C19ALOX15 | |
| 2,2'-Dihydroxybenzphenone SCHEMBL6652370 | 0.65 | LIG1 (0.64) | LMNATSHRHPGDCYP2C19ALOX15 | |
| SCHEMBL4060271 | 0.64 | LMNA (0.62) | LMNATSHRHPGDCYP2C19ALOX15 | |
| SCHEMBL7061561 | 0.64 | LMNA (0.53) | LMNATSHRHPGDCYP2C19ALOX15 | |
| SCHEMBL27485335 | 0.63 | LIG1 (0.56) | LMNAHPGDCYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3398614-B1 | AGENT FOR PREVENTING AND/OR TREATING ALZHEIMER'S DISEASE | UNIV KYOTO (JP) | 2021-07-28 | — | — | EP | disclosed |