Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385605 | 0.88 | MEN1 (0.42) | HTR6MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL31512541 | 0.88 | HTR6 (0.39) | HTR6MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL30963571 | 0.88 | MEN1 (0.42) | HTR6MEN1GFERKMT2AALDH1A1 | |
| SCHEMBL23658928 | 0.83 | HTR6 (0.42) | HTR6MEN1GFERKMT2ADRD2 | |
| SCHEMBL28566174 | 0.81 | HTR6 (0.41) | HTR6MEN1GFERKMT2ADRD2 | |
| SCHEMBL30963578 | 0.80 | MEN1 (0.40) | HTR6MEN1GFERKMT2ADRD2 | |
| SCHEMBL19385625 | 0.80 | MEN1 (0.40) | HTR6MEN1GFERKMT2ADRD2 | |
| Abeprazan SCHEMBL18196939 | 0.79 | HTR6 (0.39) | HTR6MEN1GFERKMT2ADRD2 | |
| Abeprazan SCHEMBL29719476 | 0.79 | HTR6 (0.39) | HTR6MEN1GFERKMT2ADRD2 | |
| Abeprazan SCHEMBL29443418 | 0.79 | HTR6 (0.39) | HTR6MEN1GFERKMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854784-A1 | METHOD FOR PRODUCING 4-METHOXY PYRROLE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |