Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23658928 | 0.90 | HTR6 (0.42) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL18196939 | 0.88 | HTR6 (0.39) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL29719476 | 0.88 | HTR6 (0.39) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL29443418 | 0.88 | HTR6 (0.39) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL19385615 | 0.87 | HTR6 (0.40) | HTR6DRD2MEN1GFERKMT2A | |
| SCHEMBL19385624 | 0.86 | HTR6 (0.38) | HTR6DRD2MEN1GFERKMT2A | |
| Hydrochloric Acid SCHEMBL19385754 | 0.85 | HTR6 (0.38) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL29201776 | 0.85 | HTR6 (0.38) | HTR6DRD2MEN1GFERKMT2A | |
| Abeprazan SCHEMBL29201774 | 0.84 | HTR6 (0.37) | HTR6DRD2MEN1GFERKMT2A | |
| SCHEMBL31512541 | 0.82 | HTR6 (0.39) | HTR6DRD2MEN1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602771-B | Acid addition salts of compounds | 株式会社大熊制药 | 2021-07-16 | — | — | CN | claimed |
| CN-114845701-A | Liquid pharmaceutical composition of 1- (5- (2, 4-difluorophenyl) -1- ((3-fluorophenyl) sulfonyl) -4-methoxy-1H-pyrrol-3-yl) -N-methyl-amine | 株式会社大熊制药 | 2022-08-02 | — | — | CN | disclosed |
| CN-114845701-A | Liquid pharmaceutical composition of 1- (5- (2, 4-difluorophenyl) -1- ((3-fluorophenyl) sulfonyl) -4-methoxy-1H-pyrrol-3-yl) -N-methyl-amine | 株式会社大熊制药 | 2022-08-02 | — | — | CN | disclosed |
| CN-108602771-B | Acid addition salts of compounds | 株式会社大熊制药 | 2021-07-16 | — | — | CN | disclosed |
| CN-108602772-B | Novel crystal form of 1- (5- (2, 4-difluorophenyl) -1- ((3-fluorophenyl) sulfonyl) -4-methoxy-1H-pyrrole-3-yl) -N-methylmelamine salt | 株式会社大熊制药 | 2021-06-04 | — | — | CN | disclosed |
| CN-112739684-A | Preparation method for 4-methoxy pyrrole derivative | 株式会社大熊制药 | 2021-04-30 | — | — | CN | disclosed |