Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395823 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL30584520 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| Hydrochloric Acid SCHEMBL22393215 | 0.99 | ALDH1A1 (0.53) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| Hydrochloric Acid SCHEMBL18395289 | 0.99 | ALDH1A1 (0.53) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL18396078 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL1906547 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL2736359 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL21965973 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL1906546 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLKDM4EGPR84 | |
| SCHEMBL31158206 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLKDM4EGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004167-B | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2024-03-22 | — | — | CN | claimed |
| CN-111004167-A | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2020-04-14 | — | — | CN | claimed |
| CN-111004167-B | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2024-03-22 | — | — | CN | disclosed |
| EP-3613420-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2022-05-25 | — | — | EP | disclosed |
| EP-3573981-B1 | ALKOXY BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION | UCB Biopharma SRL (BE) | 2022-03-16 | — | — | EP | disclosed |
| EP-3324958-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2021-07-28 | — | — | EP | disclosed |
| CN-111004167-A | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-107847486-A | Salts and prodrugs of 1-methyl-D-tryptophan | 新联基因公司 | 2018-03-27 | — | — | CN | disclosed |