Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828525 | 0.77 | MAPT (0.61) | CYP3A4TSHRMCOLN3MAPTCA9 | |
| SCHEMBL6828315 | 0.74 | C5AR1 (0.54) | PTPRCMCOLN3MAPTCA9POLB | |
| SCHEMBL294724 | 0.72 | TSHR (1.00) | CYP3A4TSHRMAPT | |
| SCHEMBL31361989 | 0.71 | MAPT (0.72) | CYP3A4TSHRMAPTHTTNPSR1 | |
| SCHEMBL6832001 | 0.71 | POLB (0.79) | CYP3A4MCOLN3MAPTPOLBHTT | |
| SCHEMBL6402838 | 0.70 | ALDH1A1 (0.50) | CYP3A4TSHRMCOLN3MAPTHTT | |
| SCHEMBL10788022 | 0.70 | PTPRC (0.59) | PTPRCMCOLN3MAPTCA9HTT | |
| SCHEMBL10956151 | 0.70 | CA12 (0.70) | PTPRCMCOLN3MAPTCA9HTT | |
| SCHEMBL4797335 | 0.69 | PTPRC (0.55) | CYP3A4PTPRCMCOLN3MAPTCA9 | |
| SCHEMBL6259894 | 0.69 | PTPRC (1.00) | PTPRCMCOLN3MAPTCA9AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |