Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511190 | 0.85 | CYP3A4 (0.55) | PTPRCCA12CA9F2L3MBTL1 | |
| SCHEMBL10956151 | 0.79 | CA12 (0.70) | PTPRCCA12CA9C5AR1MAPT | |
| SCHEMBL16423298 | 0.75 | LMNA (0.45) | CA12CA9F2L3MBTL1NAMPT | |
| SCHEMBL2367814 | 0.74 | CYP3A4 (0.48) | PTPRCCA12CA9C5AR1MAPT | |
| SCHEMBL894820 | 0.72 | NR1H3 (0.56) | CA12CA9F2HTTNPSR1 | |
| SCHEMBL8563717 | 0.72 | ALDH1A1 (0.48) | CA12CA9MAPTL3MBTL1ACHE | |
| SCHEMBL10788022 | 0.72 | PTPRC (0.59) | PTPRCCA12CA9C5AR1MAPT | |
| SCHEMBL3700907 | 0.71 | CA12 (0.54) | PTPRCCA12CA9C5AR1MAPT | |
| SCHEMBL7098960 | 0.71 | TP53 (0.50) | PTPRCF2MCOLN3NPSR1LMNA | |
| SCHEMBL3886338 | 0.71 | ALDH1A1 (0.62) | PTPRCCA12CA9C5AR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |