Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.42 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23678463 | 0.88 | CTSA (0.37) | PDE2AAGXTCTSAKIF11BACE1 | |
| SCHEMBL23678378 | 0.87 | PDE2A (0.37) | PDE2AAGXTCTSAKIF11BACE1 | |
| SCHEMBL23678465 | 0.86 | CTSA (0.46) | PDE2ACTSAKIF11AKR1C3AKR1C2 | |
| SCHEMBL23678310 | 0.83 | PDE2A (0.36) | PDE2AAGXTHDAC4CTSAKIF11 | |
| SCHEMBL23678478 | 0.82 | KIF11 (0.39) | PDE2AAGXTHDAC4CTSAKIF11 | |
| SCHEMBL23678375 | 0.81 | AGXT (0.43) | AGXTHDAC4KIF11BACE1FFAR1 | |
| SCHEMBL23678327 | 0.81 | AGXT (0.43) | AGXTHDAC4KIF11BACE1FFAR1 | |
| SCHEMBL23678326 | 0.81 | AGXT (0.43) | AGXTHDAC4KIF11BACE1FFAR1 | |
| SCHEMBL23678409 | 0.79 | CYP17A1 (0.41) | PDE2ATRPV3 | |
| SCHEMBL23678481 | 0.74 | ADRA2C (0.33) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854788-A1 | COMPOUND CONTAINING OXADIAZOLE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SK Biopharmaceuticals Co., Ltd. (KR) | 2021-07-28 | — | — | EP | disclosed |