SCHEMBL23679115

SCHEMBL23679115

FC(F)(F)c1cc(-c2ccc3c(c2)c2ccccc2n3-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c2)cc(C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.35
PGR P06401 1/20 0.35
ICMT O60725 3/20 0.35
ABCG2 Q9UNQ0 4/20 0.33
TACR1 P25103 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
MGLL Q99685 1/20 0.33
METAP2 P50579 1/20 0.32
PPARG P37231 2/20 0.32
PPARA Q07869 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23679097 0.98 NR3C1 (0.35) NR3C1PGRICMTABCG2TACR1
SCHEMBL20777638 0.97 ABCG2 (0.34) NR3C1PGRICMTABCG2TACR1
SCHEMBL20777471 0.97 NR3C1 (0.35) NR3C1PGRICMTABCG2TACR1
SCHEMBL23543442 0.95 NR3C1 (0.39) NR3C1PGRICMTABCG2LMNA
SCHEMBL23679046 0.95 NR3C1 (0.35) NR3C1PGRICMTABCG2TACR1
SCHEMBL23679096 0.95 NR3C1 (0.36) NR3C1PGRICMTABCG2LMNA
SCHEMBL23679039 0.95 ABCG2 (0.35) ABCG2TACR1LMNAPOLBMETAP2
SCHEMBL23679118 0.94 ABCG2 (0.33) NR3C1PGRABCG2TACR1LMNA
SCHEMBL23679176 0.94 LMNA (0.35) NR3C1PGRICMTABCG2LMNA
SCHEMBL20777483 0.94 NR3C1 (0.37) NR3C1PGRICMTABCG2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3673031-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-07-28 EP disclosed