Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 7/20 | 0.41 |
| ▸ | PNP | P00491 | 4/20 | 0.38 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427614 | 0.79 | CDK1 (0.47) | HPGDXDHPNPTK1MEN1 | |
| SCHEMBL21362203 | 0.79 | XDH (0.41) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL852107 | 0.79 | XDH (0.57) | XDHPNPTK1BLMUSP2 | |
| SCHEMBL24236963 | 0.79 | HPGD (0.46) | HPGDXDHPNPTK1BLM | |
| SCHEMBL18520809 | 0.76 | CDK2 (0.46) | HPGDXDHHPRT1 | |
| SCHEMBL22326671 | 0.76 | HPGD (0.43) | HPGDXDHPNPTK1TSHR | |
| SCHEMBL22901682 | 0.76 | HPGD (0.43) | HPGDXDHPNPTK1NT5E | |
| SCHEMBL21943445 | 0.73 | HPGD (0.42) | HPGDXDHPNPBLMHBB | |
| SCHEMBL21942694 | 0.71 | ADORA2A (0.46) | HPGDXDHPNPUSP2TSHR | |
| SCHEMBL24222086 | 0.70 | PNP (0.42) | HPGDPNPTK1BLMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3854799-A1 | CYCLIC DINUCLEOTIDE ANALOGUE, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATION | Shanghai de Novo Pharmatech Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |