Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368174 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HPGD | |
| SCHEMBL1199847 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1201534 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1199875 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1200986 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1201602 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1199892 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1231278 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1199953 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL8085074 | 0.82 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | claimed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | claimed |
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |