Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 8/20 | 0.42 |
| ▸ | THRB | P10828 | 8/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368024 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGD | |
| SCHEMBL2368175 | 0.77 | SMPD1 (0.54) | ALDH1A1HPGDTHRATHRBSMPD1 | |
| SCHEMBL2368074 | 0.73 | TLR8 (0.61) | ALDH1A1HPGDLMNA | |
| SCHEMBL12510798 | 0.73 | TLR8 (0.61) | ALDH1A1HPGDLMNA | |
| SCHEMBL6111802 | 0.73 | SMPD1 (0.41) | ALDH1A1HPGDLMNATHRATHRB | |
| SCHEMBL2247380 | 0.71 | SMPD1 (0.44) | ALDH1A1HPGDLMNATHRATHRB | |
| SCHEMBL2246934 | 0.68 | TLR8 (0.50) | LMNASMPD1 | |
| SCHEMBL6933511 | 0.68 | TLR8 (0.50) | LMNASMPD1 | |
| SCHEMBL2244311 | 0.68 | ALDH1A1 (0.57) | ALDH1A1LMNA | |
| SCHEMBL10498409 | 0.68 | SMPD1 (0.62) | ALDH1A1HPGDTHRATHRBSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | claimed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | claimed |
| WO-2011117830-A1 | DERIVATIVES OF PHENAZINE USEFUL TO TREAT CANCER | Université de la Méditerranée AIX-Marseille II (FR) | 2011-09-29 | — | — | WO | disclosed |
| EP-2368885-A1 | Derivatives of phenazine useful to treat cancer | Université de la Méditerranée (Aix-Marseille II) (FR) | 2011-09-28 | — | — | EP | disclosed |