SCHEMBL23680478

SCHEMBL23680478

NCCCC[C@H](NC(=O)[C@@H](N)CCc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LNPEP Q9UIQ6 5/20 0.66
ERAP2 Q6P179 4/20 0.66
ERAP1 Q9NZ08 3/20 0.66
MMP2 P08253 1/20 0.53
CPA1 P15085 1/20 0.50
CPA2 P48052 1/20 0.50
CPA4 Q9UI42 1/20 0.50
ECE1 P42892 1/20 0.48
MMP1 P03956 1/20 0.48
MMP3 P08254 1/20 0.48
ACE P12821 1/20 0.48
LTA4H P09960 1/20 0.48
TLR2 O60603 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30565150 0.95 LNPEP (0.60) LNPEPERAP2ERAP1MMP2CPA1
SCHEMBL7857079 0.95 LNPEP (0.60) LNPEPERAP2ERAP1MMP2CPA1
SCHEMBL1246343 0.91 LNPEP (0.55) LNPEPERAP2ERAP1MMP2CPA1
SCHEMBL7857980 0.91 LNPEP (0.55) LNPEPERAP2ERAP1MMP2CPA1
SCHEMBL29405428 0.89 LNPEP (0.55) LNPEPERAP2ERAP1MMP2CPA1
SCHEMBL29382413 0.88 ERAP2 (0.65) LNPEPERAP2ERAP1MMP2ECE1
SCHEMBL28540087 0.88 ERAP2 (0.65) LNPEPERAP2ERAP1MMP2ECE1
SCHEMBL29372662 0.88 ERAP2 (0.65) LNPEPERAP2ERAP1MMP2ECE1
SCHEMBL1711485 0.88 ERAP2 (0.65) LNPEPERAP2ERAP1MMP2ECE1
SCHEMBL170652 0.88 ERAP2 (0.65) LNPEPERAP2ERAP1MMP2ECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025083205-A1 DRUG COMBINATION COMPRISING ANTI-CD37 ANTIBODY MAYTANSINE CONJUGATE AND BCL2 INHIBITOR OR PI3K INHIBITOR DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-04-24 WO disclosed
EP-4507734-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES Debiopharm Research & Manufacturing S.A. (CH) 2025-02-19 EP disclosed
WO-2023198884-A1 LIGAND-DRUG-CONJUGATES WITH IMPROVED PHARMACOKINETIC AND DRUG RELEASE PROPERTIES DEBIOPHARM RESEARCH & MANUFACTURING S.A. (CH) 2023-10-19 WO disclosed
US-20210230218-A1 OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF MABPLEX INTERNATIONAL, LTD. (CN) 2021-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210230218-A1 OLIGOPEPTIDE LINKER INTERMEDIATE AND PREPARATION METHOD THEREOF VIP, DNPEP, PREP LNPEP 10/4885ERAP2 150/4885ERAP1 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.