Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.60 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.47 |
| ▸ | CPA2 | P48052 | 1/20 | 0.47 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30565150 | 1.00 | LNPEP (0.60) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL1246343 | 0.96 | LNPEP (0.55) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL7857980 | 0.96 | LNPEP (0.55) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL23680478 | 0.95 | LNPEP (0.66) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL30565149 | 0.90 | LNPEP (0.52) | LNPEPERAP2ERAP1MMP2LTA4H | |
| SCHEMBL29405927 | 0.88 | LNPEP (0.52) | LNPEPERAP2ERAP1MMP2CPA1 | |
| SCHEMBL1374145 | 0.88 | MMP2 (0.64) | LNPEPERAP2MMP2LTA4HACE | |
| SCHEMBL17510189 | 0.88 | MMP2 (0.64) | LNPEPERAP2MMP2LTA4HACE | |
| SCHEMBL1374146 | 0.88 | MMP2 (0.64) | LNPEPERAP2MMP2LTA4HACE | |
| SCHEMBL30688845 | 0.88 | MMP2 (0.64) | LNPEPERAP2MMP2LTA4HACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |