Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 13/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989531 | 0.84 | FGFR1 (0.65) | FGFR1 | |
| SCHEMBL2648767 | 0.84 | MEN1 (0.48) | FGFR1HPGD | |
| SCHEMBL9663546 | 0.84 | TP53 (0.51) | FGFR1HPGD | |
| SCHEMBL2653551 | 0.83 | FGFR1 (0.46) | FGFR1HPGD | |
| SCHEMBL2642029 | 0.83 | FGFR1 (0.52) | FGFR1 | |
| SCHEMBL5930067 | 0.79 | FGFR1 (0.43) | FGFR1HPGDALDH1A1 | |
| SCHEMBL2653400 | 0.79 | FGFR1 (0.47) | FGFR1HPGDALDH1A1 | |
| SCHEMBL2654409 | 0.79 | RAB9A (0.44) | FGFR1HPGDALDH1A1 | |
| SCHEMBL24329036 | 0.78 | HPGD (0.70) | FGFR1HPGDALDH1A1 | |
| SCHEMBL24329054 | 0.78 | FGFR1 (0.63) | FGFR1HPGDALDH1A1HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021151014-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |