Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 15/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989531 | 0.89 | FGFR1 (0.65) | FGFR1SRCHTT | |
| SCHEMBL2647217 | 0.87 | GABRA1 (0.60) | FGFR1KDRSRCHTT | |
| SCHEMBL2653370 | 0.86 | NT5E (0.44) | FGFR1KDRSRC | |
| SCHEMBL2641993 | 0.84 | KDR (0.57) | FGFR1KDRSRC | |
| SCHEMBL5930067 | 0.83 | FGFR1 (0.43) | FGFR1SRC | |
| SCHEMBL2654570 | 0.83 | HPGD (0.43) | FGFR1SRCHTT | |
| SCHEMBL23680876 | 0.83 | FGFR1 (0.63) | FGFR1 | |
| SCHEMBL2648767 | 0.83 | MEN1 (0.48) | FGFR1SRC | |
| SCHEMBL9663546 | 0.83 | TP53 (0.51) | FGFR1SRC | |
| SCHEMBL2654510 | 0.82 | GABRA1 (0.40) | FGFR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563001-B1 | Imidazole compounds, their preparation and use | NEUROSEARCH AS (DK) | 1996-02-28 | — | — | EP | disclosed |
| US-5360809-A | Imidazole compounds and their use as calcium channel blockers | NEUROSEARCH A/S (DK) | 1994-11-01 | — | — | US | disclosed |
| EP-0563001-A1 | Imidazole compounds, their preparation and use | NEUROSEARCH A/S (DK) | 1993-09-29 | — | — | EP | disclosed |