Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375418 | 0.86 | DPP4 (0.41) | DPP4F2RENBIRC2 | |
| SCHEMBL10704033 | 0.81 | REN (0.45) | F2RENFAPKDM4E | |
| SCHEMBL29396071 | 0.79 | BIRC2 (0.52) | BIRC2 | |
| SCHEMBL20234748 | 0.79 | BIRC2 (0.52) | BIRC2 | |
| SCHEMBL29860395 | 0.78 | CAPN1 (0.43) | F2RENKDM4E | |
| Bromide SCHEMBL30010259 | 0.78 | BIRC2 (0.51) | BIRC2 | |
| SCHEMBL23904781 | 0.77 | DPP4 (0.44) | DPP4DPP7 | |
| SCHEMBL21307631 | 0.77 | DPP4 (0.39) | DPP4F2RENBIRC2 | |
| SCHEMBL13049763 | 0.76 | DPP4 (0.61) | DPP4DPP8DPP7FAPDPP9 | |
| SCHEMBL10304320 | 0.76 | F2 (0.47) | DPP4F2RENDPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021148396-A1 | EPIDERMAL GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2021-07-29 | — | — | WO | disclosed |