Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 8/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | REN | P00797 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21307631 | 0.91 | DPP4 (0.39) | DPP4BIRC2F2RENPLAT | |
| SCHEMBL23680935 | 0.86 | DPP4 (0.43) | DPP4BIRC2F2REN | |
| SCHEMBL26465717 | 0.84 | F2 (0.45) | DPP4BIRC2F2PLATPRSS1 | |
| SCHEMBL18754852 | 0.84 | DPP4 (0.43) | DPP4BIRC2 | |
| SCHEMBL24514324 | 0.82 | PEPD (0.35) | DPP4BIRC2F2XIAPBIRC3 | |
| SCHEMBL27437988 | 0.81 | DPP4 (0.41) | DPP4BIRC2F2PLATPRSS1 | |
| SCHEMBL20234748 | 0.81 | BIRC2 (0.52) | BIRC2XIAPBIRC3 | |
| SCHEMBL29396071 | 0.81 | BIRC2 (0.52) | BIRC2XIAPBIRC3 | |
| Bromide SCHEMBL30010259 | 0.80 | BIRC2 (0.51) | BIRC2XIAPBIRC3 | |
| SCHEMBL15840457 | 0.79 | EPHX1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073106-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS INHIBITORS OF TAPS | TRACT PHARMACEUTICALS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |