SCHEMBL23682941

SCHEMBL23682941

O=C(c1ccc(N2CCC(N3CCCC3)CC2)cc1)N1CCC(N2CCCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL3 Q96JM7 19/20 1.00
▸ L3MBTL1 Q9Y468 17/20 1.00
▸ MBTD1 Q05BQ5 6/20 1.00
▸ TP53BP1 Q12888 2/20 1.00
▸ L3MBTL4 Q8NA19 2/20 1.00
▸ KDM4E B2RXH2 1/20 0.69
▸ MEN1 O00255 1/20 0.69
▸ ALDH1A1 P00352 1/20 0.69
▸ KMT2A Q03164 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13034168 0.95 L3MBTL3 (0.91) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL14529142 0.95 L3MBTL3 (0.91) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL14529143 0.92 L3MBTL3 (0.84) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682730 0.91 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL13034163 0.89 L3MBTL3 (0.80) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL23682947 0.89 L3MBTL3 (1.00) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL14528665 0.88 L3MBTL3 (0.78) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL13034196 0.86 L3MBTL3 (0.74) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL21776913 0.86 L3MBTL3 (0.75) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL13034197 0.85 L3MBTL3 (0.72) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285573-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-09-14 — — US disclosed
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-02-16 — — US disclosed
US-20210283265-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-09-16 — — US disclosed
US-20210284629-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-09-16 — — US disclosed
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-08-05 — — US disclosed
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-07-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ATXN2L, ATXN2, ATXN10 L3MBTL3 3097/4885L3MBTL1 3195/4885MBTD1 773/4885
US-20230285573-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, CBL, UBQLN2 L3MBTL3 518/4885L3MBTL1 228/4885MBTD1 2125/4885
US-20210283265-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, CBL, UBQLN2 L3MBTL3 518/4885L3MBTL1 228/4885MBTD1 2125/4885
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE CYFIP2, TPX2, ATXN2 L3MBTL3 1221/4885L3MBTL1 737/4885MBTD1 3067/4885
US-20210228723-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, F13B, GRN L3MBTL3 1368/4885L3MBTL1 718/4885MBTD1 2460/4885
US-20210284629-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE NEDD4, UBQLN2, UBTF L3MBTL3 372/4885L3MBTL1 173/4885MBTD1 1394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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