⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602684 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL22548517 | 0.80 | — | — | |
| SCHEMBL19249149 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL14586397 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL12619778 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL15706255 | 0.74 | — | — | |
| SCHEMBL20347931 | 0.73 | — | — | |
| SCHEMBL25928873 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL21536588 | 0.70 | — | — | |
| SCHEMBL6302385 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210283265-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-09-16 | — | — | US | disclosed |
| US-20210238226-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-08-05 | — | — | US | disclosed |
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |