⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25928873 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL12619778 | 0.82 | ALDH1A1 (0.39) | — | |
| SCHEMBL15471203 | 0.75 | KDM4E (0.38) | — | |
| SCHEMBL99319 | 0.74 | ALDH1A1 (0.47) | — | |
| SCHEMBL1106619 | 0.74 | DNM1 (0.39) | — | |
| SCHEMBL6308884 | 0.74 | — | — | |
| SCHEMBL20063347 | 0.72 | — | — | |
| SCHEMBL9829129 | 0.72 | — | — | |
| SCHEMBL10605776 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL6305661 | 0.72 | MAPT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891019-B2 | Protected aminofunctionalized polymerization initiators and methods of making and using same | FMC CORPORATION (US) | 2005-05-10 | — | — | US | claimed |
| US-20030162978-A1 | Protected aminofunctionalized polymerization initiators and methods of making and using same | BROCKMANN THORSTEN WERNER (US) | 2003-08-28 | — | — | US | claimed |
| US-6610859-B1 | 3-((N- benzyl-N-methyl)amino)-1-propyllithium | FMC CORPORATION | 2003-08-26 | — | — | US | claimed |
| US-20030139563-A1 | Protected aminofunctionalized polymerization initiators and methods of making and using same | BROCKMANN THORSTEN WERNER (US) | 2003-07-24 | — | — | US | claimed |
| WO-2002024764-A1 | PROTECTED AMINOFUNCTIONALIZED POLYMERIZATION INITIATORS AND METHODS OF MAKING AND USING SAME | FMC CORPORATION (US) | 2002-03-28 | — | — | WO | claimed |
| US-6891019-B2 | Protected aminofunctionalized polymerization initiators and methods of making and using same | FMC CORPORATION (US) | 2005-05-10 | — | — | US | disclosed |
| US-6875876-B2 | Protected aminofunctionalized polymerization initiators and methods of making and using same | FMC CORPORATION (US) | 2005-04-05 | — | — | US | disclosed |
| US-20030162978-A1 | Protected aminofunctionalized polymerization initiators and methods of making and using same | BROCKMANN THORSTEN WERNER (US) | 2003-08-28 | — | — | US | disclosed |
| US-6610859-B1 | 3-((N- benzyl-N-methyl)amino)-1-propyllithium | FMC CORPORATION | 2003-08-26 | — | — | US | disclosed |
| US-20030139563-A1 | Protected aminofunctionalized polymerization initiators and methods of making and using same | BROCKMANN THORSTEN WERNER (US) | 2003-07-24 | — | — | US | disclosed |
| US-20030114611-A1 | Functionalized alkyllithium formulations with improved thermal stability and processes for making the same | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20030114592-A1 | Processes for improving stability of living polymer chain ends | FMC CORPORATION | 2003-06-19 | — | — | US | disclosed |
| WO-2002024764-A1 | PROTECTED AMINOFUNCTIONALIZED POLYMERIZATION INITIATORS AND METHODS OF MAKING AND USING SAME | FMC CORPORATION (US) | 2002-03-28 | — | — | WO | disclosed |