Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717502 | 0.92 | AR (0.35) | ARHRH1KCNH2 | |
| SCHEMBL23685220 | 0.89 | ENPP2 (0.34) | AR | |
| SCHEMBL23683796 | 0.87 | MAPT (0.36) | AR | |
| SCHEMBL23717288 | 0.86 | EPHX2 (0.35) | — | |
| SCHEMBL23685219 | 0.86 | EPHX2 (0.35) | — | |
| SCHEMBL23674638 | 0.85 | AR (0.34) | ARHTR1AADRA1A | |
| SCHEMBL23674640 | 0.85 | AR (0.34) | ARHTR1AADRA1A | |
| SCHEMBL23717045 | 0.85 | POLB (0.37) | HTR1AP2RX7 | |
| SCHEMBL23685205 | 0.85 | AR (0.34) | ARHTR1AADRA1AP2RX7HRH1 | |
| SCHEMBL23685126 | 0.84 | ENPP2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150806-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |