Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | SLC5A7 | Q9GZV3 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 8/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | UGCG | Q16739 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685129 | 1.00 | AR (0.34) | ARSLC5A7KDM4EMEN1MAPK1 | |
| SCHEMBL23685199 | 0.85 | AR (0.34) | ARHRH1KCNH2HTR1AADRA1A | |
| SCHEMBL23683774 | 0.84 | AR (0.34) | ARSLC5A7HRH1KCNH2 | |
| SCHEMBL23685128 | 0.84 | AR (0.35) | ARSLC5A7HRH1KCNH2 | |
| SCHEMBL23685206 | 0.84 | AR (0.35) | ARSLC5A7HRH1KCNH2 | |
| SCHEMBL23685131 | 0.84 | AR (0.35) | ARSLC5A7HRH1KCNH2 | |
| SCHEMBL23685138 | 0.82 | AR (0.34) | ARHRH1KCNH2 | |
| SCHEMBL23195642 | 0.82 | AR (0.34) | ARSLC5A7HRH1KCNH2ADORA2A | |
| SCHEMBL23683776 | 0.81 | SLC5A7 (0.38) | SLC5A7MEN1KMT2A | |
| SCHEMBL23683769 | 0.80 | SLC5A7 (0.39) | SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150806-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |