Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 2/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6027899 | 0.89 | KDM4E (0.43) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL1759400 | 0.83 | SELL (0.54) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL28413744 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL29670017 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL12316452 | 0.81 | KDM4E (0.54) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL17779218 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL1004219 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL122472 | 0.80 | HMGB1 (0.62) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL30706280 | 0.80 | HMGB1 (0.62) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL471443 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230101-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230101-A1 | COMPOUNDS FOR TREATING DENGUE VIRUS INFECTIONS AND OTHER INFECTIONS | EIF2AK2, HAVCR2, MAVS | KDM4E 2701/4885ALDH1A1 403/4885LMNA 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.