Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | TYMP | P19971 | 3/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.51 |
| ▸ | NT5E | P21589 | 2/20 | 0.51 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.51 |
| ▸ | DUT | P33316 | 3/20 | 0.42 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655914 | 1.00 | POLB (0.62) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL1527090 | 0.96 | POLB (0.57) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL5925303 | 0.94 | POLB (0.56) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL5358852 | 0.94 | POLB (0.56) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL10491019 | 0.93 | POLB (0.54) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL11134759 | 0.92 | POLB (0.53) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL2368809 | 0.92 | POLB (0.53) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL8906384 | 0.90 | POLB (0.51) | POLBABL1RIN1TYMPP2RY6 | |
| SCHEMBL13170031 | 0.88 | POLB (0.69) | POLBABL1RIN1P2RY6NT5E | |
| SCHEMBL24115327 | 0.88 | TYMP (0.48) | POLBABL1RIN1TYMPP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807837-A | ADMINISTERING TO TREAT HIV INFECTIONS TO INHIBIT THE REPLICATION OF FOREIGN NUCLEIC ACIDS IN A NORMAL CELL | SANKYO COMPANY, LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5674856-A | TREATMENT AND PROPHYLAXIS OF VIRAL INFECTIONS, INCLUDING AIDS AND TUMORS | SANKYO COMPANY, LIMITED (JP) | 1997-10-07 | — | — | US | disclosed |
| EP-0611075-B1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| EP-0611075-A1 | Modified oligodeoxyribonucleotides, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-08-17 | — | — | EP | disclosed |