SCHEMBL236881

SCHEMBL236881

C1C[N]C(N2CCCC2)C1

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 3/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL731008 0.97
SCHEMBL2241191 0.95
SCHEMBL157427 0.92 CYP2D6 (0.33) CYP2D6MEN1KMT2ALMNA
SCHEMBL2778573 0.92
SCHEMBL2229452 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA
SCHEMBL286072 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA
SCHEMBL4712511 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA
SCHEMBL6050828 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA
SCHEMBL3658217 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA
SCHEMBL2569149 0.90 CYP2D6 (0.32) CYP2D6MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4058390-A Amine salts of phenyl-4-hydroxypyridazines and the preparation and herbicidal compositions thereof CHEMIE LINZ AKTIENGESELLSCHAFT (OE) 1977-11-15 US claimed
US-11998538-B2 Piperidine urea derivatives as soluble epoxide hydrolase inhibitors NEUROPN THERAPEUTICS (US) 2024-06-04 US disclosed
US-20240139172-A1 PIPERIDINE UREA DERIVATIVES FOR CANCER THERAPY NeuroPn Therapeutics, Inc. (US) 2024-05-02 US disclosed
WO-2024073648-A1 PIPERIDINE UREA DERIVATIVES FOR CANCER THERAPY NeuroPn Therapeutics, Inc. (US) 2024-04-04 WO disclosed
US-20240075023-A1 PIPERIDINE UREA DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS NeuroPn Therapeutics, Inc. (US) 2024-03-07 US disclosed
EP-4323341-A1 PIPERIDINE UREA DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS Neuropn Therapeutics, LLC (US) 2024-02-21 EP disclosed
US-9656955-B2 Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy ABBVIE INC. (US) 2017-05-23 US disclosed
US-9550754-B2 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2017-01-24 US disclosed
US-9365512-B2 Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy AbbVie Deutschland GmbH & Co. KG (DE) 2016-06-14 US disclosed
US-20160145197-A1 PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES ABBVIE INC. 2016-05-26 US disclosed
US-20100184820-A1 COMBINATIONS COMPRISING STAUROSPORINES NOVARTIS AG (CH) 2010-07-22 US disclosed
EP-1951213-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS Morvus Technology Ltd. (GB) 2008-08-06 EP disclosed
WO-2007074344-A1 USE OF ALPHA-HYDROXY CARBONYL COMPOUNDS AS REDUCING AGENTS MORVUS TECHNOLOGY LIMITED (GB) 2007-07-05 WO disclosed
EP-1363900-B1 ISOINDOLE-IMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF CELGENE CORP (US) 2007-01-24 EP disclosed
US-20070015662-A1 Herbicide/safener combination BAYER CROPSCIENCE GMBH (DE) 2007-01-18 US disclosed
US-6013836-A PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY ROHM AND HAAS COMPANY (US) 2000-01-11 US disclosed
WO-1995015955-A1 2,4-DIAMINOTHIAZOLES AND THEIR PRODUCTION BASF AKTIENGESELLSCHAFT (DE) 1995-06-15 WO disclosed
US-4767769-A HISTAMINE-H2 ANTAGONISTS THE BOOTS COMPANY PLC (GB) 1988-08-30 US disclosed
US-4168311-A APHIDICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-18 US disclosed
US-4066637-A BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS CIBA-GEIGY CORPORATION (US) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015662-A1 Herbicide/safener combination CYP2W1, CBR3, DDT CYP2D6 56/4885MEN1 3038/4885KMT2A 1526/4885
US-20240139172-A1 PIPERIDINE UREA DERIVATIVES FOR CANCER THERAPY PDCD1, TP53, CHEK2 CYP2D6 4456/4885MEN1 4395/4885KMT2A 925/4885
US-20240075023-A1 PIPERIDINE UREA DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS EPHX1, EPHX2, HPGDS CYP2D6 1859/4885MEN1 4837/4885KMT2A 2930/4885
US-20160145197-A1 PROCESS FOR PREPARING BICYCLIC AMINE DERIVATIVES HRH4, HRH3, HRH1 CYP2D6 1206/4885MEN1 188/4885KMT2A 410/4885
US-20100184820-A1 COMBINATIONS COMPRISING STAUROSPORINES MCL1, FLT3, BCL3 CYP2D6 4810/4885MEN1 2244/4885KMT2A 137/4885
US-11998538-B2 Piperidine urea derivatives as soluble epoxide hydrolase inhibitors EPHX1, EPHX2, HPGDS CYP2D6 1859/4885MEN1 4837/4885KMT2A 2930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.