SCHEMBL23690158

SCHEMBL23690158

Clc1cc(Cl)c2c(oc3ccccc32)c1I

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 10/20 0.50
SMN1; SMN2 Q16637 2/20 0.41
TTR P02766 1/20 0.40
MAOA P21397 3/20 0.37
KDM5A P29375 1/20 0.37
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
CASP7 P55210 2/20 0.36
HSD17B10 Q99714 2/20 0.36
MEN1 O00255 1/20 0.36
ALPI P09923 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
CASP3 P42574 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
CASP6 P55212 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22379484 0.81 MAOA (0.43) AHRSMN1; SMN2MAOAKDM5AKDM4E
SCHEMBL23690159 0.79 AHR (0.50) AHRSMN1; SMN2TTRKDM4EMAPT
SCHEMBL22892836 0.79 AHR (0.46) AHRSMN1; SMN2TTRMAOAKDM5A
SCHEMBL23690166 0.78 AHR (0.58) AHRSMN1; SMN2TTRMAOAKDM4E
SCHEMBL23690156 0.78 AHR (0.68) AHRSMN1; SMN2TTRKDM4EMAPT
SCHEMBL6388502 0.76 AHR (0.67) AHRSMN1; SMN2TTR
SCHEMBL29833195 0.76 AHR (0.51) AHRSMN1; SMN2TTRMAOAKDM4E
SCHEMBL23611394 0.76 AHR (0.51) AHRSMN1; SMN2TTRMAOAKDM4E
SCHEMBL23623460 0.76 AHR (0.51) AHRSMN1; SMN2TTRMAOAKDM4E
SCHEMBL24296577 0.76 AHR (0.51) AHRSMN1; SMN2TTRMAOAKDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210234104-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-29 US disclosed