SCHEMBL23690159

SCHEMBL23690159

Nc1c(Cl)cc(Cl)c2c1oc1ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.50
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 4/20 0.42
GAA P10253 4/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
HPGD P15428 3/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
NQO1 P15559 1/20 0.42
MGAM O43451 2/20 0.40
SI P14410 2/20 0.40
MGAM2 Q2M2H8 2/20 0.40
LIMK1 P53667 1/20 0.40
TTR P02766 1/20 0.40
RET P07949 1/20 0.40
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23690158 0.79 AHR (0.50) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL23690166 0.78 AHR (0.58) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL23690156 0.78 AHR (0.68) AHRKDM4EALDH1A1SMN1; SMN2HPGD
SCHEMBL23560207 0.77 AHR (0.72) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL24524554 0.77 AHR (0.53) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL30169074 0.77 KDM4E (0.47) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL6388502 0.76 AHR (0.67) AHRSMN1; SMN2TTR
SCHEMBL24296577 0.76 AHR (0.51) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL7333549 0.76 ALDH1A1 (0.49) AHRKDM4EALDH1A1GAASMN1; SMN2
SCHEMBL7312519 0.76 TTR (0.48) AHRKDM4EALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210234104-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-29 US disclosed