Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 18/20 | 0.53 |
| ▸ | MMP13 | P45452 | 16/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23673495 | 0.88 | MMP13 (0.53) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23693583 | 0.88 | MMP12 (0.53) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23693528 | 0.88 | MMP13 (0.60) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23693194 | 0.88 | MMP13 (0.60) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL4424736 | 0.87 | MMP13 (0.70) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL27540150 | 0.87 | MMP13 (0.70) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23693177 | 0.87 | MMP12 (0.53) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23673437 | 0.85 | MMP13 (0.60) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23673538 | 0.85 | MMP13 (0.54) | MMP12MMP13KDM4EMMP2MMP3 | |
| SCHEMBL23673542 | 0.85 | MMP13 (0.54) | MMP12MMP13KDM4EMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |