Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 13/20 | 0.59 |
| ▸ | CTSL | P07711 | 7/20 | 0.59 |
| ▸ | CTSB | P07858 | 4/20 | 0.55 |
| ▸ | CTSS | P25774 | 4/20 | 0.55 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23693746 | 1.00 | CTSK (0.59) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL23693691 | 0.88 | CTSK (0.57) | CTSKCTSLCTSBCTSS | |
| SCHEMBL23693525 | 0.88 | CTSK (0.57) | CTSKCTSLCTSBCTSS | |
| SCHEMBL23693155 | 0.88 | CTSK (0.58) | CTSKCTSLCTSBCTSS | |
| SCHEMBL23693869 | 0.88 | CTSK (0.58) | CTSKCTSLCTSBCTSS | |
| SCHEMBL23693866 | 0.86 | CTSK (0.58) | CTSKCTSLCTSBCTSSCTSV | |
| SCHEMBL23693607 | 0.86 | CTSL (0.71) | CTSKCTSLCTSBCTSS | |
| SCHEMBL23693796 | 0.86 | CTSL (0.64) | CTSKCTSLCTSBCTSS | |
| SCHEMBL29887096 | 0.85 | CTSK (0.57) | CTSKCTSLCTSBCTSS | |
| SCHEMBL29887065 | 0.85 | CTSK (0.57) | CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |