Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21756078 | 0.93 | MAPT (0.47) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL12800978 | 0.90 | CSNK2A2 (0.53) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL12440983 | 0.90 | MAOB (0.44) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL2628177 | 0.86 | CSNK2A2 (0.58) | CSNK2A2CSNK2BCSNK2A1MAPTCYP3A4 | |
| SCHEMBL10141873 | 0.86 | MAOB (0.47) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL30693959 | 0.86 | PIM1 (0.48) | CSNK2A2CSNK2BCSNK2A1MAPTKCNH2 | |
| SCHEMBL3771900 | 0.86 | PIM1 (0.48) | CSNK2A2CSNK2BCSNK2A1MAPTKCNH2 | |
| SCHEMBL22271444 | 0.86 | MAPT (0.47) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL22738448 | 0.84 | MAOB (0.46) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT | |
| SCHEMBL19155599 | 0.82 | MAPT (0.47) | CSNK2A2CSNK2BCSNK2A1MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368520-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-04-26 | — | — | EP | disclosed |
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |