SCHEMBL12800978

SCHEMBL12800978

Cc1ccc2oc3ccc(Br)cc3c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CSNK2A2 P19784 1/20 0.53
▸ CSNK2B P67870 1/20 0.53
▸ CSNK2A1 P68400 1/20 0.53
▸ MAPT P10636 3/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ TP53 P04637 2/20 0.50
▸ CYP3A4 P08684 2/20 0.50
▸ RECQL P46063 1/20 0.50
▸ MAOB P27338 2/20 0.47
▸ PIM1 P11309 1/20 0.46
▸ KCNH2 Q12809 1/20 0.45
▸ KMT2A Q03164 1/20 0.43
▸ CA12 O43570 1/20 0.42
▸ CA9 Q16790 1/20 0.42
▸ ALDH1A1 P00352 3/20 0.42
▸ HTT P42858 1/20 0.42
▸ CASP6 P55212 1/20 0.42
▸ KDM4E B2RXH2 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21756078 0.90 MAPT (0.47) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL23693655 0.90 CSNK2A2 (0.49) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL19217398 0.89 CSNK2A2 (0.62) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL258689 0.87 PIM1 (0.55) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL1610145 0.87 MAPT (0.50) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL16925876 0.84 ESR2 (0.52) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL10144943 0.83 CSNK2A2 (0.41) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL1637246 0.82 PIM1 (0.52) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL19155599 0.82 MAPT (0.47) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1
SCHEMBL22271444 0.82 MAPT (0.47) CSNK2A2CSNK2BCSNK2A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 — — US disclosed
EP-3368520-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-26 — — EP disclosed
WO-2021147882-A1 DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF 深圳信立泰药业股份有限公司 2021-07-29 — — WO disclosed
WO-2021121230-A1 COMPOUND, APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME 北京鼎材科技有限公司 2021-06-24 — — WO disclosed
EP-3835299-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME LG Chem, Ltd. (KR) 2021-06-16 — — EP disclosed
EP-3345983-B1 COMPOUNDS CONTAINING AT LEAST ONE DISILYL COMPOUND SELECTED FROM DISILYLCARBAZOLES, DISILYLDIBENZOFURANS, DISILYLDIBENZOTHIOPHENES, DISILYLDIBENZOPHOSPHOLES, DISILYLDIBENZOTHIOPHENE S-OXIDES AND DISILYLDIBENZOTHIOPHENE S, S-DIOXIDES UDC IRELAND LTD (IE) 2020-08-26 — — EP disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 — — EP disclosed
EP-3061759-B1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO (JP) 2019-12-25 — — EP disclosed
EP-3174885-B1 2,9-FUNCTIONALIZED BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLES AS HOSTS FOR ORGANIC LIGHT EMITTING DIODES (OLEDS) IDEMITSU KOSAN CO (JP) 2019-10-02 — — EP disclosed
EP-2993215-B1 Azabenzimidazo[2,1-a]benzimidazoles for electronic applications IDEMITSU KOSAN CO (JP) 2019-06-19 — — EP disclosed
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS IDEMITSU KOSAN CO., LTD. (JP) 2016-08-25 — — US disclosed
US-20160190480-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2016-06-30 — — US disclosed
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-08-27 — — US disclosed
US-20150207083-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-07-23 — — US disclosed
US-8962779-B2 Method of forming polyaryl polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2015-02-24 — — US disclosed
US-20150031847-A1 METHOD OF FORMING POLYARYL POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2015-01-29 — — US disclosed
US-20140252280-A1 4H-IMIDAZO[1,2-A]IMIDAZOLES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-09-11 — — US disclosed
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications BASF SE (DE) 2012-09-27 — — US disclosed
US-7323458-B1 Dihydrobenzodiazepins and their use for treating dyslipidemia MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-01-29 — — US disclosed
US-7323458-B1 Dihydrobenzodiazepins and their use for treating dyslipidemia MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120241681-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications EIF4A1, ITPR2, ITPR1 CSNK2A2 389/4885CSNK2B 1050/4885CSNK2A1 312/4885
US-20150243907-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 CSNK2A2 1937/4885CSNK2B 2110/4885CSNK2A1 1992/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 CSNK2A2 725/4885CSNK2B 1523/4885CSNK2A1 611/4885
US-20160190480-A1 4H-Imidazo[1,2-a]imidazoles for Electronic Applications PAH, NISCH, KCNH1 CSNK2A2 1294/4885CSNK2B 2391/4885CSNK2A1 1317/4885
US-20160248026-A1 NITRILE SUBSTITUTED DIBENZOFURANS DBF4, NXF1, NCF1 CSNK2A2 2789/4885CSNK2B 2324/4885CSNK2A1 2151/4885
US-20150207083-A1 BENZIMIDAZO[1,2-A]BENZIMIDAZOLE DERIVATIVES FOR ELECTRONIC APPLICATIONS PAICS, EIF4A1, ECI1 CSNK2A2 725/4885CSNK2B 1523/4885CSNK2A1 611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback