SCHEMBL10141873

SCHEMBL10141873

Cc1ccc2c(c1)oc1ccc(C)cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
ALDH1A1 P00352 5/20 0.46
HPGD P15428 3/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 6/20 0.44
HTT P42858 2/20 0.44
KDM4E B2RXH2 5/20 0.43
HSD17B10 Q99714 3/20 0.43
CYP3A4 P08684 3/20 0.43
TP53 P04637 2/20 0.43
NQO1 P15559 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 1/20 0.43
ALOX15 P16050 1/20 0.43
MAPK1 P28482 2/20 0.42
KCNH2 Q12809 1/20 0.42
CDC25A P30304 1/20 0.42
CDC25C P30307 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22738448 0.98 MAOB (0.46) MAOBALDH1A1HPGDGAAMAPT
SCHEMBL22271444 0.95 MAPT (0.47) MAOBALDH1A1HPGDMAPTHTT
SCHEMBL13309573 0.92 MAOB (0.50) MAOBALDH1A1HPGDGAAMAPT
SCHEMBL19155599 0.91 MAPT (0.47) MAOBALDH1A1HPGDMAPTHTT
SCHEMBL15195120 0.91 MAOB (0.50) MAOBALDH1A1HPGDGAAMAPT
SCHEMBL9927267 0.91 MAOB (0.53) MAOBALDH1A1HPGDGAAMAPT
SCHEMBL1610145 0.91 MAPT (0.50) ALDH1A1HPGDMAPTHTTKDM4E
SCHEMBL10133858 0.90 MAOB (0.51) MAOBALDH1A1HPGDGAAMAPT
SCHEMBL10133855 0.90 MAOB (0.47) MAOBALDH1A1HPGDMAPTHTT
SCHEMBL23626076 0.86 MAOB (0.53) MAOBALDH1A1HPGDGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US claimed
EP-4063368-B1 NITROGEN-CONTAINING COMPOUND AND ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2024-06-26 EP disclosed
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-11744151-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-29 US disclosed
US-20230212335-A1 Polymeric Compound, Electroluminescent Device Material, Electroluminescent Device, and Electronic Device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-06 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2023-07-04 US disclosed
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed
US-20220165958-A1 Compound and an Organic Semiconducting Layer, an Organic Electronic Device, a Display Device and a Lighting Device Comprising the Same NOVALED GMBH (DE) 2022-05-26 US disclosed
US-20220069230-A1 Compound and Organic Electronic Device Comprising the Same NOVALED GMBH (DE) 2022-03-03 US disclosed
US-8933110-B2 Hepatitis C virus inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2015-01-13 US disclosed
US-8785487-B2 Hepatitis C virus inhibitors ENANTA PHARMACEUTICALS, INC. (US) 2014-07-22 US disclosed
EP-2518110-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION Sumitomo Chemical Company, Limited (JP) 2012-10-31 EP disclosed
US-20120256537-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-11 US disclosed
US-20120256537-A1 COMPOSITION AND LIGHT EMITTING ELEMENT USING THE COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-11 US disclosed
US-20120076755-A1 Hepatitis C Virus Inhibitors ENANTA PHARMACEUTICALS, INC. 2012-03-29 US disclosed
US-20120039848-A1 HEPATITIS C VIRUS INHIBITORS ENANTA PHARMACEUTICALS, INC. 2012-02-16 US disclosed
US-20110189129-A1 HEPATITIS C VIRUS INHIBITORS ENANTA PHARMACEUTICALS, INC. 2011-08-04 US disclosed
US-4042603-A SUBSTITUTED DIBENZOFURAN OR 9-FLUORENONE FROM A DIPHENYL ETHER OR BENZOPHENONE UBE INDUSTRIES, LTD. (JA) 1977-08-16 US disclosed
US-4016156-A DISTYRYL-DIBENZOFURANES USED AS OPTICAL BRIGHTENERS ON CELLULOSE AND POLYAMIDE MATERIALS CIBA-GEIGY CORPORATION (US) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120039848-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, SLC10A1, EIF2AK2 MAOB 1610/4885ALDH1A1 365/4885HPGD 1806/4885
US-20220165958-A1 Compound and an Organic Semiconducting Layer, an Organic Electronic Device, a Display Device and a Lighting Device Comprising the Same OCIAD1, AOX1, OCIAD2 MAOB 68/4885ALDH1A1 18/4885HPGD 2237/4885
US-11691983-B2 Specifically substituted benzofuro- and benzothienoquinolines for organic light emitting diodes KCNQ2, KCNQ1, KCNQ4 MAOB 205/4885ALDH1A1 865/4885HPGD 2093/4885
US-11744151-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, JUND MAOB 137/4885ALDH1A1 1283/4885HPGD 832/4885
US-20220069230-A1 Compound and Organic Electronic Device Comprising the Same ESR1, ESRRA, RER1 MAOB 1490/4885ALDH1A1 59/4885HPGD 3952/4885
US-20110189129-A1 HEPATITIS C VIRUS INHIBITORS HAVCR2, HCCS, NSUN2 MAOB 173/4885ALDH1A1 901/4885HPGD 2335/4885
US-20120076755-A1 Hepatitis C Virus Inhibitors NSUN2, HCCS, HAVCR2 MAOB 156/4885ALDH1A1 984/4885HPGD 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.