Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27147943 | 0.92 | TTR (0.53) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL69226 | 0.89 | TTR (0.68) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30175920 | 0.89 | TTR (0.68) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2628175 | 0.84 | TTR (0.70) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11768568 | 0.81 | TTR (0.65) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10110990 | 0.81 | CA12 (0.45) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9927267 | 0.80 | MAOB (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL16714053 | 0.80 | TTR (0.84) | TTRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10623602 | 0.79 | TTR (0.83) | TTRALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL2013077 | 0.79 | TTR (0.53) | TTRALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021147882-A1 | DIBENZOFURAN DERIVATIVE CATHEPSIN K INHIBITOR, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2021-07-29 | — | — | WO | disclosed |